Disease-causing bacteria genetically engineered to produce medicine

commonly we hear about E. coli bacterium when there ’s an irruption of food for thought toxic condition . But now a group of engineers have turned these disease - causing bugs into a “ production platform ” for antibiotics .

Genetic engineers have been trying for a while to pluck the genes of E. coli so that they ’ll produce the powerful antibiotic erythromycin A , which is used to cure infections . Producing E-Mycin A has historically been a costly and hard process . But if E. coli can reliably bring forth the medicament , researchers say it would be a major breakthrough – not just for companies who want to produce Ethril A more cheaply , but also for other engineer hope to use E. coli to synthesize other practice of medicine as well .

Science Daily reports :

Greenworks

The bacteria Saccharopolyspora erythraea , which is found in the stain , naturally produces several variants of erythromycin . Erythromycin A is the most coarse and most biologically active .

Because of the challenges associated with engineering Saccharopolyspora erythraea , researchers have hop to reach the complete production of erythromycin A using E. coli . More than 20 enzymes must play in concert to create the erythromycin A molecule . This familial and biochemical complexity stool synthesis notoriously hard . Previous research had report industry of erythromycin A intermediates in E. coli but not the concluding production .

viaChemistry and BiologyandScience Daily

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